Table 1.
entry | substrate | product | yield, % (ratiob) |
---|---|---|---|
1 |
3a |
3b |
93 (1:1) |
2 |
4a |
4b |
57 |
3 |
5a |
5b |
91 (4:1) |
4 |
6a |
6b |
63 (single isomer) |
5 |
7a |
7b |
56 (1.7:1) |
6 |
8a |
8b |
28 (1.5:1) |
7 |
9a |
9b |
47 (single isomer) |
8 |
10a |
10b |
40 (single isomer) |
9 |
1a |
1b |
78 (single isomer) |
10 |
11a |
11b |
65 (2.8:1) |
11 |
12a |
12b |
19 (single isomer) |
Conditions: MeOH, undivided cell, C anode/cathode, Et4NOTs or LiClO4.
Ratios approximated by 1H NMR; except where shown, diastereomeric structures were not determined.