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Cochrane analyses of the efficacy of azathioprine (AZA) / 6-mercaptopurine (6-MP) and methotrexate (MTX). NNT: Number needed to treat, NNH: Number needed to harm. NR: not reported. 27–30
| Number of trials | Patients (drug+placebo) | NNT | NNH | |
|---|---|---|---|---|
| AZA/6-MP Induction | 8 | 425 | 5 | 14 |
| MTX Induction | 1 | 141 | 5 | NR |
| AZA/6-MP Maintenance | 7/1 | 550 | 6/4 | 20 |
| MTX Maintenance | 3 | 98 | 4 | NR |
