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. 2015 Nov 2;10(11):e0141457. doi: 10.1371/journal.pone.0141457

Fig 2. Ebi is involved in the cellular defense response against bacterial infection.

Fig 2

Susceptibility to Enterobacter cloacae in flies of each genotype was assessed. Flies were infected with E. cloacae by pricking, and the percentage of surviving flies 2 days after infection was calculated. Error bars denote standard error. The experiment was performed four times. Both Cg-Gal4/+ (control) flies (A) and Imd mutant flies (B) showed increased sensitivity to bacterial challenge. Cg-Gal4>ebi RNAi, in which ebi expression was inhibited, showed enhanced lethality to bacterial challenge (C). Data represent the mean ± SD. *p < 0.05; **p < 0.01. NC: not challenged (not pricked); mock: mock infection (pricked with a clean needle); infected: infected by pricking the insect with a pin inoculated with bacteria.