Table 4.
Association of SNPs in the SNCA 521bp region with LB pathology in AD
| rs Number | *Map position(bp) |
#MAF Case,Control |
Assoc. allele |
LBV/AD (p) | OR | 95% CI |
|---|---|---|---|---|---|---|
| rs2298728 | Chr4:90742815 | 0.117, 0.050 |
A |
0.0004 | 2.6 | 1.54–4.41 |
| rs35897584 | Chr4:90742692 | 0.093, 0.066 | G | 0.32 | 1.44 | 0.71–2.91 |
| rs17016251 | Chr4:90742639 | 0.472, 0.435 | C | 0.30 | 1.16 | 0.87–1.55 |
Total no., N=482; LBV/AD-Lewy body variant of Alzheimer’s disease
Map position based on dbSNP b126 build
MAF, the minor allele frequency