Table 1.
All | Women | Women | Person-years | P Value* | |
---|---|---|---|---|---|
Women | Without Cancer | With Cancer | Of Follow-up | Between groups | |
(N) | 53,859 | 53,409 | 450 | 262,309 | |
Age at cancer diagnosis (mean years, SD) | 40.8 ± 5.7 | ||||
Age at Start of ART Treatment (mean years, SD) | 35.3 ± 5.3 | 35.3+5.3 | 37.8 ± 5.4 | <0.0001 | |
(%) <30 | 14.4 | 14.4 | 7.1 | 38,841 | |
31-34 | 30.0 | 30.1 | 19.1 | 81,164 | |
35-37 | 20.4 | 20.4 | 19.6 | 54,091 | |
38-40 | 17.7 | 17.7 | 24.4 | 44,910 | |
41-42 | 11.8 | 11.8 | 16.4 | 29,477 | |
≥43 | 5.7 | 5.7 | 13.3 | 13,826 | |
(%) Parity | |||||
0 | 77.5 | 77.6 | 74.9 | 202,859 | 0.27 |
1 | 14.1 | 14.0 | 16.7 | 37,289 | |
≥2 | 8.4 | 8.4 | 8.4 | 22,161 | |
Infertility Diagnosis (%), more than one is possible | |||||
Male factor | 32.8 | 32.8 | 31.8 | 86,981 | 0.69 |
Endometriosis | 9.1 | 9.2 | 8.4 | 25,379 | 0.68 |
PCOS | 12.7 | 12.7 | 10.7 | 35,538 | 0.91 |
Diminished Ovarian Reserve | 22.2 | 22.1 | 31.1 | 54,714 | <0.0001 |
Tubal factors | 20.2 | 20.2 | 17.1 | 54,322 | 0.11 |
Uterine factors | 5.2 | 5.2 | 6.2 | 13,267 | 0.34 |
Other factors | 14.9 | 14.9 | 20.9 | 39,626 | 0.0007 |
Unexplained | 12.3 | 12.4 | 10 | 32,837 | 0.15 |
(%) Number of Diagnoses | |||||
1 | 75.3 | 75.4 | 70.4 | 195,396 | 0.02 |
>1 | 24.7 | 24.6 | 29.3 | 66,913 | |
Number of Cycles (%) | |||||
1 | 51.1 | 51.1 | 48 | 126,957 | 0.45 |
2 | 26.1 | 26.2 | 25.6 | 69,729 | |
3 | 12.4 | 12.4 | 14.7 | 34,680 | |
4 | 5.5 | 5.5 | 6.4 | 16,259 | |
≥5 | 4.9 | 4.8 | 5.3 | 14,684 | |
Cumulative dose of FSH Stimulation (%) | |||||
none | 7.7 | 7.7 | 12.2 | 20,017 | 0.0003 |
<2,000 IU | 19 | 19.0 | 14.4 | 49,525 | |
2,000-3,999 IU | 29.8 | 29.9 | 26 | 76,791 | |
4,000-6,999 IU | 21.6 | 21.6 | 22.4 | 56,061 | |
7,000+ IU | 21.8 | 21.8 | 24.9 | 59,915 | |
ART Outcome: Live birth | 49.1 | 49.2 | 44.4 | 132,594 | 0.12 |
Conception, no live birth | 7.5 | 7.5 | 8.9 | 19,459 | |
No conception | 43.3 | 43.3 | 46.7 | 110,256 |
P-values calculated from chi-square test or two-sample t-test (age)