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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Gynecol Oncol. 2015 Sep 14;139(2):228–235. doi: 10.1016/j.ygyno.2015.09.011

Table 2.

Average treatment-free interval (TFI) given platinum treatment and the most recent TFI.

Median (95% CI) treatment free interval (PFI) given platinum treatment and the previous PFI.

First Re-treatment Months previous PFI <7.4 7.4–15.7 >15.7
# Intervals
 Platinum 19 19 25
 Non-platinum 59 12 9

Median (95% CI)
 Platinum 4.1 (1.9–12.2) 4.6 (3.5–13.5) 6.1 (3.4–12.6)
 Non-platinum 1.1 (0.9–2.3) 1.2 (0.8-NA) 1.0 (0.7-NA)
 Log-rank Test p=0.0263 p=0.0003 p=0.0018

Later Re-treatment Months previous PFI <7.4 7.4–15.7 >15.7

# Intervals
 Platinum 8 9 3
 Non-platinum 46 15 5

Median (95% CI)
 Platinum 3.6 (1.2-NA) 2.6 (0.9-NA) 3.4 (3.2-NA)
 Non-platinum* 1.0 (0.9–1.2) 2.2 (1.0–8.8) 0.7 (0.7-NA)
 Log-rank test p=0.1450 p=0.7640 p=0.0136

Log-rank p-values test platinum vs. non-platinum TFI in a given stratum.

NA: indicates n upper bound that cannot be evaluated.

*

significant difference across PFI levels, p=0.0363.