TABLE 2.
Ovarian Morphology in Adolescent Subjects with PCOS Measured by MRI vs. US Imaging Modalities
| MRI (N=33) |
US (N=33) |
p -value | |
|---|---|---|---|
| Number Ovaries | 66 | 66 | |
| Median (IQR) OV(cm3) | 11.9 (7.7) | 8.8 (7.8) | 0.05 |
| Mean ±SD OV(cm3) | 14.0 ± 9.1 | 11.0 ± 8.6 | 0.05 |
| % (number) of ovaries with OV >10 cm3 (Rotterdam)a | 65% (43) | 42% (28) | <0.001 |
| % (number) of ovaries with OV >14 cm3 (Kenigsberg et al) | 32% (21) | 24% (16) | NS |
| Median (IQR) FNPS (2–9mm) | 13 (5) | N/A | |
| Mean ± SD, FNPS (2–9mm) | 13.0 ± 4.0 | N/A | |
| % (number) of ovaries with FNPS ≥12 (Rotterdam) | 67% (44) | N/A | |
| % (number) of ovaries with FNPS ≥9 (Lujan et al) | 85% (56) | N/A | |
| % (number) of ovaries with FNPS ≥17 (Kenigsberg et al) | 18% (12) | N/A | |
| % (number) of ovaries with peripheral distribution of follicles | 61% (40) | 44% (28)b | NS |
| % (number) of subjects with at least 1 polycystic ovary based on Rotterdam criteria (OV >10 cm3 or FNPS ≥12) | 91% (30) | 52% (17) | 0.004 |
| % (number) of subjects with at least 1 polycystic ovary based on Lujan et al criteria (OV >10 cm3 or FNPS ≥9) | 94% (31) | 52% (17) | <0.001 |
| % (number) of subjects with at least 1 polycystic ovary based on Kenigsberg et al criteria (OV>14 cm3 or FNPS ≥17) | 64% (21) | 39% (13) | 0.04 |
a
Based on follicle count from Rotterdam criteria
b
Unable to evaluate on 3 ovaries thus denominator is 63 not 66
OV = Ovarian Volume; FNPS = Follicle Number Per Section; NS = Not Significant; N/A =cannot be determined. US= ultrasound, MRI =magnetic resonance imaging