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. 2015 Nov;185(11):2875–2885. doi: 10.1016/j.ajpath.2015.07.003

Figure 5.

Figure 5

X-Gal staining in the condylar cartilage of TM joints in mice. Intensive X-gal staining cells (blue color) are observed in the bottom layer of condylar cartilage in TM joints of AgcCreERT2+/−,Rosa26+/floxlacZ mice at the ages of 1 (B and F) and 6 (D and H) months. The black dashed lines in F and H indicates the border between the condylar cartilage and subchondral bone. No X-gal staining cells are in the top layer of the condylar cartilage in TM joints, which is consistent with the structural characteristics of the condylar cartilage of TM joints by Safranin O/Fast Green staining (I and J). X-Gal staining cells are absent in the cartilage of TM joints in the control mice (A, C, E, and G). TM, temporomandibular.