Table 1.

Ocular signs suggestive of endogenous endophthalmitis [13, 42]

Positive	Possible	Probable
Uveal tissue abscesses	Hypopyon ≤ 1.5 mm	Conjunctival injection/chemosis
Hypopyon ≥ 1.5 mm	Vitreous haze but no visible exudates	Anterior chamber inflammation but no hypopyon
Vitreous exudates	Non-necrotizing, focal, discrete chorioretinal lesions	Absence of vitreous haze
Visible arteriolar septic emboli	Optic neuritis	Lid edema
Necrotizing retinitis	Intra-retinal hemorrhages	Fever
Perivascular hemorrhages with inflammatory infiltrate	Neonate with white reflexa
Panophthalmitis	Scleritis
Corneal infiltrates or ulcer

Varying combination of symptoms may be present

^aIn a neonate presenting with white reflex, endogenous endophthalmitis can be considered in the differential diagnosis