Table 2.

Efficacy outcomes in study groups

	Group D (DEX)	Group C (control)	p value
Diazepam consumption in 24 h, mg	20 (20–30)	40 (40–50)	<0.001
Cumulative diazepam consumption, mg	60 (50–60)	90 (80–100)	<0.001
Time of target sedation, %	90 (90–95)	64.5 (60–72.5)	<0.001
Time of insufficient sedation, %	7.75 (5–10)	15 (10–20)	<0.001
Time of oversedation, %	2 (0–5)	15 (10–20)	<0.001
Rescue sedation boluses, no. in 24 h	1.25 (0–4)	4 (3–6)	0.004
Sedation stops, no. in 24 h	0 (0–1)	2 (0–3)	0.001
Communication with patient	9 (7–10)	6 (5–6)	<0.001
OAA/S scale	1 (0–2)	2 (1–4)	0.03
Haloperidol use, no. of patients (%)	2/32 (6)	10/32 (31)	0.02
Median cumulative haloperidol dose, mg	50 (IQR 40–55)	60 (IQR 40–65)	0.2

Value expressed as medians (Interquartile Ranges 25 to 75), unless otherwise specified

No number, OAA/S Observer’s Assessment of Alertness/Sedation