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. 2015 Nov 3;5:16053. doi: 10.1038/srep16053

Figure 1. IL-17 expression is associated with MVD, and IL-17 promotes in vitro tube formation in HUVECs.

Figure 1

(a) IL-17-positive cells expression and MVD staining for CD34 in NSCLC tissues (magnification, 200×). (b) Quantification of stains of immunohistochemistry; 5 random high-powered fields per section were counted for number of CD34-stained vessels intensity and distribution; Date are expressed as means; Student′s t test; *p < 0.05. (c) Significant positive correlations were found between the IL-17 expression and MVD. Spearman′s rank correlation coefficient; r = 0.471; p < 0.001. (d) Representative photographs (left panel) and mean numbers of tube length (right panel) at ×100 magnification. HUVECs were seeded on Matrigel-coated plates incubated with IL-17 (10 ng/ml, 50 ng/ml or 100 ng/ml) or vehicle control at 37 °C for 8 h (n = 3). *p < 0.05.