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. 2015 Nov 3;5:16020. doi: 10.1038/srep16020

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DADS supplementation elevated p53 and p21 expression which regulated DNA repair. At the mean time, administration with DADS prevented Tap73/ΔNp73 expression which regulated apoptosis, and consequently down regulated Bax/Bcl-2 ratio, cytochrome c release and caspase-3 expression in mouse testis exposed to carbon ion irradiation.