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. 2015 Nov 3;5:15940. doi: 10.1038/srep15940

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Copyright © 2015, Macmillan Publishers Limited

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The polymerase activities of reconstituted RNP complexes composed of the PB2, PB1, PA, and NP plasmids of the virus strains P0 (B/Florida/04/06) and P17 (MA). The indicated combinations and single-point mutants are shown. Note that PB2 and PB1 are the same in all complexes because no mutation was observed in this gene. The luciferase activity values are the mean values of at least three assays; (A) 33 °C and (B) 37 °C. *indicates P < 0.0001, and ‡indicates P < 0.01 compared with the parent virus (P0).