Table 1. Nucleotide and amino acid changes in wild-type and mouse-adapted influenza virus B/Florida/04/2006.
Genesegment | Changed nucleotidesa |
Changed amino acidsb |
||||
---|---|---|---|---|---|---|
Position | Original | Mouse- adapted | Position | Original | Mouse-adapted | |
HA | 951 | T | A | 317 | P | — |
1271 | A | G | 424 | D | G | |
M1c | 719 | A | C | 240 | N | T |
BM2c | 27 | C | T | 9 | I | — |
NP | 40 | A | G | 14 | N | S |
882 | G | C | 294 | K | N | |
PA | 1825 | G | A | 609 | V | I |
aNumbering of nucleotides is relative to B/Lee/40 and begins at the start of the non-coding region of the RNA segment.
bNumbering of amino acids is relative to B/Lee/40 and begins at the start of the coding region.
cRNA segment 7 encodes two polypeptides, M1 and BM2, using tandem cistrons.