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Induced response to H2O2 and TGF-β1 in HK-2. Increased 8-oxoG staining was observed in HK-2 cells induced by H2O2 and TGF-β1 (a). Apoptotic cells with positive TUNEL staining increased after H2O2 treatment, but not after TGF-β1 treatment (b). Increased α-SMA expression and EMT in HK-2 cells was induced by TGF-β1, but not H2O2 (c).
