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Histological analysis in kidneys from UUO mice. Representative microscopy images of sham-operated kidneys and UUO kidneys for 3 days and 10 days with HE staining (a) and Masson staining (b). Collagen deposition was significantly higher in UUO mice than sham-operated kidneys ((c), P < 0.001). The immunoreactivity of 8-oxoG was shown in UUO kidneys (d) and 8-oxoG intensity increased in UUO kidneys compared to sham controls ((e), P < 0.001).
