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. 2015 Nov 3;8:63. doi: 10.3389/fnmol.2015.00063

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Copyright © 2015 Wemhöner, Kanyshkova, Silbernagel, Fernandez-Orth, Bittner, Kiper, Rinné, Netter, Meuth, Budde and Decher.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-expression of HCN1 or WAG-HCN1 with other HCN family members. (A) Representative current traces of the co-expression of HCN1 or WAG-HCN1 with HCN2. (B) Co-expression with WAG-HCN1 causes a significant decrease in current amplitude analyzed at -130 mV. The number of experiments are indicated in the bar graphs. (C) Co-expression of WAG-HCN1 with HCN4 shows a significant decrease in current amplitude analyzed at -130 mV. The number of experiments are indicated in the bar graphs. (D) Relative current amplitudes (at +40 mV) for Kv1.1 after co-expression with HCN1 or WAG-HCN1 with HCN2. The number of experiments are indicated in the bar graphs. ^∗∗∗p < 0.001.