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. 2015 Nov 3;5:16109. doi: 10.1038/srep16109

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(A) Application of NE (100 μg/1ml, i.p.) once daily for 7 consecutive days significantly increased TRPV1 expression in T13-L2 DRGs when compared NS treated-rats. (B) An example from a cell showing responses to capsaicin (CAP, 1 μM) before and after incubation of NE (10 μM) for 5 minutes. (C) Bar graph showing a potentiation of CAP-induced Ca²⁺ transients in colon specific DRG neurons by NE. *p < 0.05, compared with CAP.