Table 2.

Gene Ontology enrichment of up- and down-regulated protein lists. The most significant five enriched GO classes are shown for the up- and down-regulated proteins

Regulation	GO ID	Gene Ontology	FDR q-value	Proteins contributing
Up-regulated	GO:0006090	pyruvate metabolic process	6.40E-01	Ldhb, Pgk1, Gapdh, Tpi1, Ldha, Pgam1, Pkm, Eno1
	GO:0006733	oxidoreduction coenzyme metabolic process	3.49E-01	Ldhb, Pgk1, Gapdh, Tpi1, Ldha, Pgam1, Pkm, Eno1, Taldo1, Tkt, Prdx5
	GO:0046496	nicotinamide nucleotide metabolic process	1.40E-01	Ldhb, Pgk1, Gapdh, Tpi1, Ldha, Pgam1, Pkm, Eno1, Taldo1, Tkt, Prdx5
	GO:0006757	ATP generation from ADP	4.47E-01	Pgk1, Gapdh, Tpi1, Ldha, Pgam1, Pkm, Eno1
	GO:0006096	glycolytic process	3.84E-01	Pgk1, Gapdh, Tpi1, Ldha, Pgam1, Pkm, Eno1
Down-regulated	GO:0006415	translational termination	1.31E-18	Rps24, Rpl24, Rps3, Rpl19, Rpl18A, Rpl18, Rps16, Rpl13A, Rps15A, Rpl15, Rpl13, Rps18, Rpl7A, Rps8, Rpl34,Rps14, Rpl6, Rps28, Rpl4, Rps6, Rpl3
	GO:0022411	cellular component disassembly	2.45E-18	Same as above
	GO:0043624	cellular protein complex disassembly	3.79E-18	Same as above
	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.66E-18	Same as above
	GO:0006613	cotranslational protein targeting to membrane	6.13E-18	Same as above