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C57BL/6 mice instilled with MWCNTs demonstrated increases in A) pulmonary resistance (R) and C) Newtonian resistance (Rn) compared to 10% Saline/Surfactant treated animals, while no change in R and Rn occurred in IL-33−/− mice (B and D) 30 days following exposure. All values are expressed as mean ± SEM (C57BL/6 n=18/group; IL-33−/− n=8/group). *p < 0.05, compared to C57BL/6 10% surfactant saline.
