Table 3.

Final Models of Correlates of Peripheral Muscle Weakness (Grip Strength Assessment) N = 120

	Screening model with sedation frequency		Screening model with sedation intensity		Final model
Parameter	βeta(se(β))	p-value	βeta(se(β))	p-value	βeta(se(β))	p-value
APACHE III	−.12(.07)	.09	−.12(.07)	.09
Age	−.23(.09)	.01*	−.23(.09)	.02*	−.24(.08)	.004*
Female gender	−10.7(2.7)	<.001*	−10.6(2.7)	<.001*	−10.4(2.5)	<.001*
Sepsis	−1.1(4.6)	.80	−1.1(4.6)	.81
Continuous Insulin infusion	−3.6(2.8)	.18	−3.6(2.7)	.19
Neuromuscular blockade	−.33(4.5)	.94	−.38(4.6)	.93
Steroids	2.3(2.8)	.42	2.2(2.8)	.43
Total ICU Days	.20(.16)	.20	.21(.16)	.20
Days on Protocol	−.19(.20)	.33	−.18(.19)	.35	−.04(.18)	.82
Days on ventilator	−.54(.19)	.007*	−.53(.19)	.007*	−.34(.12)	.005*
Sedation Frequency	−.005(.20)	.98
Sedation Intensity			.09(.29)	.77

APACHE III = Acute physiology, age, and chronic health evaluation

Sedation frequency = any sedative or analgesic administered in a 4-hour time block summed over 24 hours

Sedation intensity = aggregate score summed over 24 hours