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. 2015 Oct 28;8(5):368–375. doi: 10.1016/j.tranon.2015.07.003

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

SUV39H2 knockdown induced apoptosis. (A) Assessment of caspase 3 activation by Western blot and (B) representative figure showing Annexin V and PI staining post SUV39H2 siRNA(#2 and 4) or control siRNA transfection in Jurkat, CEM, REH, and RS4;11 (the numbers represent the percentage of total cells). (C) Graphical quantification of average Annexin V and PI staining results in Jurkat, CEM, REH, and RS4;11 from two independent experiments. Data are presented as mean ± SE; P values were calculated using Student’s t test (*P < .05; ** P < .01; ***P < .001).