Table 2.

Cox regression analyses. The table summarizes results of Cox regression analyses in the AGO-OVAR-15 subgroup genetics trial with regard to rs11623866 genotype, the respective treatment arms and survival (PFS and OS)

	FNTB rs11623866 G > C Genotype
	GG		GC		CC
	HR (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Progression-free survival
Treatment
TC	1		1		1
LTC	6.242 (2.01, 19.41)	0.002	1.046 (0.44, 2.50)	0.919	1.456 (0.32, 6.62)	0.627
Overall survival
Treatment
TC	1		1		1
LTC	9.589 (1.89, 48.54)	0.006	1.080 (0.40, 2.91)	0.881	0.474 (0.04, 5.35)	0.546

CI, confidence interval;

HR, hazard ratio;

LTC, lonafarnib + TC;

TC, taxane (paclitaxel) + carboplatin.