Table 4.
Genotype and allele distributions of MMP-2 and MMP-9 single nucleotide polymorphisms.
| Controls n (%) | Patients n (%) | OR (95% CI) | P value (2-tail) | |
|---|---|---|---|---|
| MMP-2 (-1306 C/T)† | ||||
| CC | 46 (76.7) | 51 (73.9) | ||
| CT | 10 (16.7) | 17 (24.6) | ||
| TT | 4 (6.7) | 1 (1.4) | ||
| (CC, CT+TT) | 0.862 (0.385–1.927) | 0.718 χ2 = 0.1305 | ||
| C | 102 (85) | 119 (86.2) | ||
| T | 18 (15) | 19 (13.8) | ||
| C, T | 1.105 (0.55–2.219) | 0.778 χ2 = 0.0792 | ||
| MMP-9(-1562C/T)‡ | ||||
| CC | 34 (56.7) | 40 (58.8) | ||
| CT | 23 (38.3) | 25 (36.8) | ||
| TT | 3 (5) | 3 (4.4) | ||
| (CC, CT+TT) | 1.092 (0.541–2.206) | 0.805 χ2 = 0.0608 | ||
| C | 91 (75.8) | 105 (77.2) | ||
| T | 29 (24.2) | 31 (22.8) | ||
| C, T | 1.079 (0.605–1.926) | 0.796 χ2 = 0.0669 | ||
†
One tumour sample was missed
‡
Two tumour samples were missed