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Effect of endotoxin on HAEC responses to APM. Polymyxin B, a inhibitor of bacterial endotoxin, did not suppress Sum06 APM-induced CYP1A1, TIPARP, ALDH1A3, CEBPD, and augmented PTGS2, ATF3, E-selectin expression. CCL-2 and CXCL-2 expression was significantly suppressed by polymyxin B. n = 3; *P ≤ 0.05, and Sum06 APM treatment compared with control; #P ≤ 0.05 and Sum06 APM with polymyxin compared with Sum06 APM.
