Table 3.
Summary of genome-wide responses of HAEC to APM exposure
APM in HAEC | Total Genes Affected, n | Total Genes Affected, % | Upregulated | Downregulated |
---|---|---|---|---|
Summer 2006 | 20 | 0.15 | 20 | 0 |
Winter 2007 | 5 | 0.04 | 4 | 1 |
All data are based on 13,000 probe set present in human aortic endothelial cells (HAEC). The criterion for selection was ≥ ± 2-fold change as detailed in material and methods. Effects of APM on gene expression in either HAEC were obtained by comparing the entire list of genes from HAEC grown on basal media. The number differentially expressed, either summer 2006 or winter 2007 APM-sensitive genes (column 2), is also shown as the % of the total number of genes detected (column 3). The same genes may be involved in different functions.