Table 4.
Upregulated genes affected by summer 2006 and winter 2007 APM exposure in HAEC
| Fold Change |
||||
|---|---|---|---|---|
| Gene Title | Gene Symbol | Gene ID | Summer 2006 | Winter 2007 |
| AhR-responsive genes | ||||
| Cytochrome P450, family 1, subfamily A, polypeptide 1 | CYP1A1 | NM_000499 | 3.7 | 2.3 |
| Aldehyde dehydrogenase 1 family, member A3 | ALDH1A3 | NM_000693 | 2.0 | |
| Prostaglandin-endoperoxide synthase 2 | PTGS2 | NM_000963 | 2.8 | 2.0 |
| TCDD-inducible poly(ADP-ribose) polymerase | TIPARP | AL556438 | 2.0 | |
| SAPK/JNK/NF-κB pathways | ||||
| Activating transcription factor 3 | ATF3 | NM_001674 | 3.0 | |
| B-cell CLL/lymphoma 3 | BCL3 | NM_005178 | 2.0 | |
| CCAAT/enhancer binding protein (C/EBP), delta | CEBPD | M83667 | 2.3 | |
| CCAAT/enhancer binding protein (C/EBP), delta | CEBPD | AV655640 | 2.0 | |
| Proinflammatory responses | ||||
| Chemokine (C-C motif) ligand 2 | CCL2 | S69738 | 2.3 | |
| Chemokine (C-X-C motif) ligand 2 | CXCL2 | M57731 | 2.5 | |
| Selectin E | SELE | NM_000450 | 2.8 | |
| Tumor necrosis factor, alpha-induced protein 3 | TNFAIP3 | NM_006290 | 2.1 | |
| Collagen, type I, alpha 1 | COL1A1 | K01228 | 2.5 | |
| Collagen, type I, alpha 2 | COL1A2 | NM_000089 | 2.0 | |
| Suppressor of cytokine signaling 3 | SOCS3 | BG035761 | 2.6 | |
| Phospholipase A2, group IVA (cytosolic, calcium-dependent) | PLA2G4A | M68874 | 2.1 | |
| Endothelial cell-specific response | ||||
| Apolipoprotein L domain containing 1 | APOLD1 | NM_030817 | 2.8 | |
| Solute carrier family 7, member 2 | SLC7A2 | NM_003046 | 2.0 | |
AhR, arylhydrocarbon receptor.