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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Am J Transplant. 2015 Feb 19;15(5):1241–1252. doi: 10.1111/ajt.13098

Figure 4. Increasing macrophage infiltration over 24 hours is independent of gal presence.

Figure 4

A. At 1 and 24 hours, there is no significant difference in macrophage presence between islet phenotypes (1h p=0.52, 24h p=0.36). However, there was a significant increase in both WT (p<0.01) and GTKO (p<0.01) islets from 1 to 24 hours.

B. Representative group of GTKO islets surrounded by macrophages with minimal infiltration at one hour.

C. GTKO islets from two different animals demonstrating infiltration of macrophages within the islets clusters by 24 hours.