Figure 5. Temporal summary of WT and GTKO NPIs within the dual islet transplantation model.
Findings over 24 hours for WT (a) and GTKO (b) NPIs, an asterisk (*) denotes a statistically significant difference observed from 1 to 24 hours. Both islet phenotypes demonstrated slightly diminished insulin release, decrease in antibody binding, minimal changes in complement deposition and platelet aggregation, a slight decrease in neutrophil infiltration and an increase in macrophage infiltration.