Table 2.
Members, hazard ratios, and p values of the 4-miRNA signature predicting development of melanoma brain metastasis derived from Cox proportional hazards modeling.
| HR (95% CI)* | P-value | |
|---|---|---|
| hsa-miR-150–5p | 0.31 (0.14, 0.68) | 0.003 |
| hsa-miR-15b-5p | 4.50 (1.48, 13.68) | 0.008 |
| hsa-miR-16–5p | 0.11 (0.03, 0.45) | 0.002 |
| hsa-miR-374b-3p | 0.57 (0.39, 0.84) | 0.004 |
| stage | 2.95 (1.43, 6.06) | 0.003 |
Hazard ratios (HR) and 95% confidence intervals (CI) of the standardized miRNA expressions obtained from the discovery cohort.