Skip to main content
. Author manuscript; available in PMC: 2016 Oct 21.
Published in final edited form as: Neurosci Lett. 2015 Sep 10;607:46–51. doi: 10.1016/j.neulet.2015.09.005

Figure 3.

Figure 3

Flupirtine pretreatment effectively blocks hypoxia-induced electroclinical seizures. (A) All the P10 rat pups treated with vehicle 15 minutes before exposure to hypoxic environment developed electroclinical seizures during hypoxia. In contrast none of the rats treated with 35 mg/kg of flupirtine exhibited electroclinical seizures. (B) The box and whisker plot shows the percent of time spent by the rats treated with vehicle or 35 mg/kg of flupirtine in electroclinical seizures during hypoxia. n = 6 for both vehicle and flupirtine treatment groups. *Statistically different from vehicle treated rats exposed to hypoxia. *P<0.005, Fisher's exact test for the data presented in A, and Mann Whitney test for the data presented in B was used to determine the statistical significance. Hy = Hypoxia, Veh = Vehicle, Flup = Flupirtine.