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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Clin Cancer Res. 2015 Jun 16;21(21):4922–4934. doi: 10.1158/1078-0432.CCR-15-0217

Fig. 2. The re-expression of miR-195 inhibits invasion and migration, but promotes apoptosis of LNCaP and DU145 cells in vitro.

Fig. 2

(A). miR-195 was re-expressed in the miR-195-stably transfected cell lines LNCaP and DU145. miR-195 levels were determined by qRT–PCR after transfection. miR-195 expression (miR-195/U6) was calculated as the fold change relative to the negative control (NC). (B). Transwell analysis showed that miR-195 overexpression suppressed invasive abilities of LNCaP and DU145 cells. Statistical analysis was performed with three independent experiments. (C). Woundhealing assays indicated that miR-195 upregulation inhibited migration of LNCaP and DU145 cells. Statistical analysis was performed with three independent experiments. (D). Enforced expression of miR-195 promoted the cell apoptosis of LNCaP and DU145 cells. Statistical analysis was performed with three independent experiments. Data were presented as Mean ± SD. *P<0.05, **P<0.01 compared with negative control.