A) Cleaved caspase 8 levels in CTCL cell lines as quantitated in untreated controls (NT), cells post 48h incubation with 100 nM MTX, cells 24 hours after conventional PDT, and cells following ePDT; *p < 0.01 as compared to conventional PDT. B) MIA-based quantitation of cleaved caspase 9 in CTCL cell lines in untreated controls (NT), post 48h incubation with 100 nM MTX, and 24 hours after conventional PDT versus ePDT. *p < 0.01 as compared to conventional PDT.