Table 1.

Characteristics of the initial and final models tested and their respective value of objective function. A decrease in 3.84 point in objective function is required to consider a statistically significant change for the addition of another parameter.

	Parameters	Objective function
Base model	A0, AL, ω2A0, ω2AL	10080.595
LCR–SURG + variability	A0, AL, AL-LCR,SURG ω2A0, ω2AL	10051.031

A₀: baseline parameter.

A_L: slope parameter.

A_L-LCR,SURG: slope parameter in the group of low capacity runner animals undergoing surgery.

ω²A₀: estimation of interindividual variability for A₀ baseline parameter.

ω²A_L: estimation of interindividual variability for A_L, slope parameter.