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. 2015 Nov 4;5:78. doi: 10.3389/fcimb.2015.00078

Figure 5.

Figure 5

Proximity heat map of genes required for respiratory melioidosis. The Tn-seq lung data set was filtered for genes required by B. pseudomallei at a 15-fold reduction cut off relative to the input pool (548 genes). Genes were sorted for their arrangement on the two circular chromosomes of the B. pseudomallei genome, with similar distribution density found on the larger chromosome 1 (309 genes) and smaller chromosome 2 (239 genes). The heat map provides graphical cluster analysis of gene hits located in close proximity (red = 1 gene distance) or distal hits (green >70 gene neighbor distance). The three largest genetic clusters of hits separated by no more than 4 genes per hit are indicated: capsular polysaccharide (CPS I), Type 3 Secretion System cluster 3 (T3SS3), and Type 6 Secretion System cluster 5 (T6SS5).