Table 1. Association between the GRP78 expression in the tumor tissues and the clinicopathologic variables of PDAC.
Variable | GRP78 expression | p value* | |
---|---|---|---|
No. of cases | Low high | ||
Age (years) | 0.361 | ||
≥65 | 62 | 37 25 | |
<65 | 118 | 62 56 | |
Gender | 0.566 | ||
Male | 113 | 64 49 | |
Female | 67 | 35 32 | |
Tumor location | 0.876 | ||
Head | 101 | 54 47 | |
Body/tail | 67 | 35 32 | |
Tumor size | 0.079 | ||
>4 cm | 76 | 35 41 | |
≤4 cm | 94 | 56 38 | |
Histological grade | 0.406 | ||
G1–2 | 120 | 62 58 | |
G3 | 37 | 22 15 | |
pT stage | 0.026 | ||
T1–2 | 96 | 58 38 | |
T3–4 | 74 | 32 42 | |
pN stage | 0.487 | ||
N0 | 95 | 52 43 | |
N1 | 71 | 35 36 | |
Perineural invasion | 0.111 | ||
Positive | 84 | 40 44 | |
Negative | 87 | 52 35 |
Note: The boldface type indicates a significant difference. PDAC, pancreatic ductal adenocarcinoma; G1, well differentiated; G2, moderately differentiated; G3, poorly differentiated; T, tumor; N, lymph node. * Chi-square test.