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. 2015 Nov 4;5:16244. doi: 10.1038/srep16244

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(A,C) Immunohistochemical staining for MMP-9 (A) and MMP-13 (C) at weeks 1 and 2. High numbers of MMP-9- and MMP-13-positive cells are observed in the vegf group. (B,D) Comparison of the percentages of MMP-9- (B) and MMP-13-positive cells (D) between the groups. The percentages of MMP-9- and MMP-13-positive cells are significantly higher in the vegf group than in the control and sham groups (*P < 0.05).