Table 1. Summary of clinical parameters of the enrolled individuals.

	CCA (n = 103)	BBDD (n = 34)	Healthy Control (n = 20)
Male n (%)	55 (53.3)	22 (64.7)	12 (60.0)
Age (median, range)	58 (33, 83)	45 (20, 78)	45 (19, 83)
Laboratory values (median, range)
Tbil (μmol/L)	183 (9, 493)	78 (33, 135)*	11 (9, 15)*
AST (U/L)	94 (69, 212)	31 (27, 45)*	19 (16, 23)*
ALT (U/L)	101 (35, 368)	22 (13, 37)*	17 (14, 26)*
CA19-9 (U/ml)	205 (1, 1000)	42 (12, 56)*	23 (6, 31)*

^*mean p < 0.01 compared with CCA group.

CCA: cholangiocarcinoma, BBDD: benign bile-duct disease, Tbil: total bilirubin, AST: aspartate transaminase, ALT: alanine aminotransferase, CA19-9: carbohydrate antigen 19-9.