Table 3.
Overall basal IL-6 secretion after forskolin synchronization in human myotubes.
Non-obese (n = 3) |
Obese (n = 3) |
All donors (n = 6) |
|
---|---|---|---|
Mean ± SEM | Mean ± SEM | Mean ± SEM | |
IL-6/48h in siControl samples (pg) | 4386.54 ± 411.71 | 5888.25 ± 1547.86 | 5137.40 ± 796.43 |
IL-6/48h in siClock samples (pg) | 1424.12 ± 408.83 | 2395.52 ± 625.60 | 1909.82 ± 385.20 |
Inhibition of secretion (%) | 69.30 ± 10.61 | 59.66 ± 7.04 | 64.48 ± 6.09 |
Clock mRNA silencing (%) | 91.32 ± 2.67 | 78.57 ± 8.15 | 84.94 ± 4.57 |