Table 2.
List of attributes derived from neuropsychological test and neuroimaging measures.
| Neuropsychological and neuroimaging measures | |
|---|---|
| Average FDG-PET of angular, temporal, and posterior cingulate | Mini Mental State Examination-baseline |
|
| |
| Average PIB SUVR of frontal cortex, anterior cingulate, precuneus cortex, and parietal cortex | Ventricles measure |
|
| |
| Average AV45 SUVR of frontal, anterior cingulate, precuneus, and parietal cortex relative to the cerebellum | Hippocampus-baseline, volume |
|
| |
| Clinical dementia ratio-SB | Whole brain-baseline, volume |
|
| |
| ADAS 11 | UCSF entorhinal-baseline, volume |
|
| |
| ADAS 13 | UCSF fusiform-baseline, volume |
|
| |
| Mini Mental Scale Examination score | UCSF Med Temp-baseline |
|
| |
| RAVLT (forgetting) | UCSF ICV-baseline |
|
| |
| RAVLT (5 sum) | MOCA-baseline |
|
| |
| Functional Assessment Questionnaire | Pt ECog-Memory-baseline |
|
| |
| MOCA | Pt ECog-Language-baseline |
|
| |
| Pt ECog-Memory | Pt ECog-Vis/Spat-baseline |
|
| |
| Pt ECog-Language | Pt ECog-Plan-baseline |
|
| |
| Pt ECog-Visual | Pt ECog-Organ-baseline |
|
| |
| Pt ECog-Plan | Pt ECog-Div atten-baseline |
|
| |
| Pt ECog-Organ | Pt ECog-Total-baseline |
|
| |
| Pt ECog-Div atten | SP ECog-Mem-baseline |
|
| |
| Pt ECog-Total | SP ECog-Lang-baseline |
|
| |
| SP ECog-Memory | SP ECog-Vis/Spat-baseline |
|
| |
| SP ECog-Language | SP ECog-Plan-baseline |
|
| |
| SP ECog-Visual | SP ECog-Organ-baseline |
|
| |
| SP ECog-Plan | SP ECog-Div atten-baseline |
|
| |
| SP ECog-Organ | SP ECog-Total-baseline |
|
| |
| SP ECog-Attention | Average FDG-PET of angular, temporal, and posterior cingulate at baseline |
|
| |
| SP ECog-Total | Average PIB SUVR of frontal cortex, anterior cingulate, precuneus cortex, and parietal cortex at baseline |
|
| |
| UCSF ventricles measures | Average AV45 (PET ligand) SUVR of frontal, anterior cingulate, precuneus, and parietal cortex relative to the cerebellum at baseline |
|
| |
| UCSF hippocampus measure | CDR-SB |
|
| |
| UCSF whole brain measure | ADAS 11, baseline |
|
| |
| UCSF entorhinal measure | ADAS 13, baseline |
|
| |
| UCSF fusiform measure | |
|
| |
| UCSF temporal measure | RAVLT (forgetting), baseline |
|
| |
| UCSF ICV | RAVLT (5 sum), baseline |
Pt: patient, ECog: everyday cognition test, SP: study partner, ADAS: Alzheimer's disease assessment scale, MOCA: Montreal Cognitive Assessment, Ray Auditory Verbal Learning Test, ICV: intracranial volume, SUVR: Standard Uptake value ratio, and CDR-SB: Clinical Dementia Rating Sum of Boxes.