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. Author manuscript; available in PMC: 2015 Nov 4.
Published in final edited form as: Lancet Infect Dis. 2015 Mar 16;15(6):692–702. doi: 10.1016/S1473-3099(15)70024-1

Figure 3. Risk of recrudescence by day 28 in Africa and Asia.

Figure 3

The predicted risk of recrudescence by day 28 for a given enrolment parasitaemia and total lumefantrine dose in Africa and Asia. The risks were estimated using the coefficients for parasitaemia and lumefantrine dose from a Cox’s model containing age, dose, and baseline parasitaemia for Africa. For Asia, the model contained dose and baseline parasitaemia. We assumed zero study effects. The horizontal line represents the 5% treatment failure rate threshold from WHO that should be used to assess if a new drug can be introduced for treatment of uncomplicated malaria. The vertical line is the parasitaemia of 100 000 per μL, a threshold used in the multivariable models for calculating the population-attributable risk estimates.