Figure 1.

The expression of FBP1 directly correlates with c-Myc in nasopharyngeal carcinoma. (a) Western blots of normal human nasopharyngeal epithelial cell samples (N03 and N06) and samples of nasopharyngeal carcinoma cell lines using antibodies against FBP1 and c-Myc (left panel). The relationship between FBP1 and c-Myc is shown in the right panel. β-Actin was used as a control for protein loading and integrity. (b) FBP1 and c-Myc mRNA levels in a series of NPC cell lines compared with the normal human nasopharyngeal epithelial cells. mRNA levels are presented as the means±S.D. and are normalized to the housekeeping gene β-actin using qRT-PCR. (c) The relative expression of FBP1 and c-Myc in 29 pairs of matched NPC and non-tumor tissues at the transcript level (left and middle panels). The right panel shows the association between FBP1 and c-Myc