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. 2015 Oct 15;6(10):e1920. doi: 10.1038/cddis.2015.258

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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FBP1 silencing reduced the tumorigenicity of NPC cells. (a) Images of the tumors formed by CNE2 cells transfected with NC or siFBP1. (b) The growth curve of tumors formed by CNE2 cells transfected with NC or siFBP1. The data are presented as the means±S.D. (n=6 mice in each group). (c–d) HE staining pictures of mice treated with NC (c) or with siFBP1 (d) (SP x400). (e–f) IHC staining pictures of FBP1 expression in the primary xenografts from cells treated with NC (e) or with siFBP1 (f) (SP x400). (g–h) IHC staining pictures of c-Myc expression in the primary xenografts from cells treated with NC (g) or with siFBP1 (h) (SP x400)