Table 3. Multivariate analysis with the COX proportional hazards for the predictor of OS and PFS of the NPC.
| Prognostic factors | P-value | HR |
95% CI for HR |
|
|---|---|---|---|---|
| Lower | Upper | |||
| OS | ||||
| Age (years; >46 versus ≤46) | 0.170 | 0.420 | 0.122 | 1.450 |
| Gender (female versus male) | 0.982 | 1.105 | 0.267 | 3.864 |
| T stage (T3–4 versus T1–2) | 0.866 | 0.872 | 0.178 | 4.276 |
| N stage (N2–3 versus N0–1) | 0.401 | 0.553 | 0.139 | 2.220 |
| Clinical stage (III–IV versus I–II) | 0.048 | 1.900 | 0.984 | 6.399 |
| c-Myc (high versus low) | 0.031 | 0.512 | 0.063 | 4.151 |
| FBP1 (high versus low) | 0.039 | 1.405 | 0.680 | 4.268 |
| PFS | ||||
| Age (years; >46 versus ≤46) | 0.055 | 0.376 | 0.138 | 1.021 |
| Gender (female versus male) | 0.340 | 1.623 | 0.600 | 4.386 |
| T stage (T3–4 versus T1–2) | 0.453 | 0.558 | 0.122 | 2.559 |
| N stage (N2–3 versus N0–1) | 0.186 | 0.480 | 0.161 | 1.424 |
| Clinical stage (III–IV versus I–II) | 0.823 | 1.352 | 0.097 | 18.832 |
| c-Myc (high versus low) | 0.240 | 0.384 | 0.123 | 1.194 |
| FBP1 (high versus low) | 0.014 | 0.958 | 1.330 | 6.037 |
Abbreviations: CI, confidence interval; FBP1, far upstream element-binding protein 1; HR, hazard ratio; OS, overall survival; PFS, progression-free survival