Table 3. Classification and intracellular localization of L. major proteins interacting with LmjMCAa.
| Group | Protein | Intracellular localization |
|---|---|---|
| Ser/Thr protein kinases | LmjF.13.1640: mitogen-activated protein kinase 7, putative | Cytoplasm |
| LmjF.26.2440: protein kinase, putative | Cytoplasm | |
| Proteases | LmjF.27.0500: calpain-like cysteine peptidase, putative | Cytoplasm |
| LmjF.36.5560: aminopeptidase P1, putative | GPI-anchored | |
| Vesicle transport | LmjF.10.1160: Rab1 small GTP-binding protein | Cytoplasm |
| LmjF.22.1110: dynein heavy chain, cytosolic, putative | Cytoplasm | |
| LmjF.36.3150: ADP-ribosylation factor GTPase activating protein, putative | Cytoplasm | |
| LmjF.36.6430: transport protein sec23-like | Cytoplasm | |
| Metabolism | LmjF.06.0950: glucosamine-fructose-6-phosphate aminotransferase, putative | Cytoplasm |
| LmjF.18.0510: aconitase, putative | Cytoplasm/mitochondrion | |
| LmjF.26.1620: Cdp-diacylglycerol synthetase-like protein | Membrane | |
| LmjF.32.2950: nucleoside diphosphate kinase b | Cytoplasm | |
| LmjF.36.0150: fructose-6-phosphate2-kinase/fructose-2,6-bisphosphatase-like protein | Cytoplasm | |
| LmjF.36.3910: S-adenosyl homocysteine hydrolase | Cytoplasm | |
| LmjF.36.6460: tartrate-sensitive acid phosphatase acp-3.2, putative | Cytoplasm | |
| Nucleotide binding | LmjF.04.0330: mitochondrial exoribonuclease DSS-1, putative | Mitochondrion |
| LmjF.05.0530: kinetoplast-associated protein-like protein | Kinetoplast | |
| LmjF.09.0360: DNA photolyase, putative | Nucleus | |
| LmjF.23.0730: RNA-binding protein, putative | GPI-anchored | |
| LmjF.32.1400: DEAD/DEAH box helicase-like protein, putative | Cytoplasm/nucleus |
Reiterative proteins were found in more than one life cycle stage of L. major parasites (in bold)
a
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