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. 2015 Oct 22;6(10):e1938. doi: 10.1038/cddis.2015.304

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The compound loss of BOK/BAX/BAK in the hematopoietic compartment leads to an increase in peripheral blood lymphocytes. Blood analysis from sick TKO (n=19) and DKO (n=19) chimeras and healthy wt controls (n=9) was performed using the ADVIA automated machine to determine the numbers of (a) lymphocytes, (b) monocytes, (c) neutrophils, (d) eosinophils, (e) red blood cells and (f) platelets. Bar graphs depict the mean±S.E.M. of the total numbers of cells of a particular subset. P-values above brackets indicate significant differences (i.e., P<0.05)