Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 22;6(10):e1938. doi: 10.1038/cddis.2015.304

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

TKO hematopoietic chimeras display substantial lymphocytic infiltration in several organs. (a) Summary of the incidence of lymphocytic infiltration (scored on a scale of 0–3) into the indicated organs. Bar graphs represent mean±S.E.M of score for each tissue from mice reconstituted with wt (n=4), Bax^−/−Bak^−/−DKO (n=9) or Bok^−/−Bax^−/−Bak^−/−TKO (n=11) FLCs, P<0.05. Tissues were harvested at the time when mice were sick (for DKO and TKO chimeras) or at termination of the experiment (for wt controls). (b) Representative H&E stained sections depicting leukocyte infiltration in the lung, liver, salivary glands, stomach and small intestine of mice reconstituted with FLCs of the indicated genotype. Arrows indicate areas of infiltration (Magnification: × 5)