Table 6.
Risk of progression of Coronary Calcium Score according to pulse pressure and brachial-ankle pulse wave velocity odds ratioa (95 % CI) of CAC change >0 by PWV50 % and pulse pressure 50 %
| Number | Cases | Age and sex-adjusted ORa (95 % CI) | Multivariate-adjusted ORa (95 % CI) | ||
|---|---|---|---|---|---|
| Model 1 | Model 2 | ||||
| Pulse pressure | |||||
| Pulse pressure <50 % | 574 | 159 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Pulse pressure ≥50 % | 550 | 159 | 1.01 (0.77–1.32) | 0.91 (0.68–1.21) | 0.90 (0.63–1.28) |
| Pulse Pressure and Pulse Wave Velocity | |||||
| PWV <50 % and pulse pressure <50 % | 322 | 66 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| PWV <50 % and pulse pressure ≥50 % | 240 | 44 | 0.90 (0.58–1.39) | 0.85 (0.54–1.33) | 0.90 (0.55–1.46) |
| PWV ≥50 % and pulse pressure <50 % | 252 | 93 | 2.01 (1.37–2.95) | 1.82 (1.22–2.72) | 1.88 (1.26–2.82) |
| PWV ≥50 % and pulse pressure ≥50 % | 310 | 115 | 1.88 (1.30–2.72) | 1.57 (1.06–2.32) | 1.75 (1.09–2.80) |
| P for trend | <0.001 | 0.002 | <0.001 | ||
OR odds ratio, CI confidence interval
aEstimated from logistic regression. Multivariable model 1 was adjusted for age, sex, center, year of screening exam, smoking status, alcohol intake, educational level, BMI, diabetes, hypertension, HDL, LDL and glucose; model 2: model 1 plus adjustment for sbp and heart rate