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. 2015 Sep 24;7(10):8261–8273. doi: 10.3390/nu7105391

Table 3.

Plasma, erythrocytes parameters and cognition according to APOE rs7412.

Biomarkers and Cognition rs7412 p Value
T/C + T/T (n = 64) C/C (n = 368)
Plasma
Glu (mmol/L) 5.623 (5.197, 6.049) 5.394 (5.214, 5.575) 0.332
TG (mmol/L) 1.654 (1.432, 1.876) 1.545 (1.451, 1.639) 0.375
TC (mmol/L) 4.772 (4.551, 4.993) 4.846 (4.753, 4.940) 0.543
LDL-C (mmol/L) 2.985 (2.775, 3.195) 3.298 (3.210, 3.387) 0.007
HDL-C (mmol/L) 1.376 (1.292, 1.459) 1.327 (1.291, 1.362) 0.290
MDA (nmol/L) 6.552 (5.172, 7.932) 6.960 (6.376, 7.543) 0.593
T-AOC (activity U/L) 10.488 (9.436, 11.459) 11.773 (11.356, 12.190) 0.018
Retinol (μg/mL) 0.728 (0.695, 0.762) 0.724 ( 0.709, 0.738) 0.800
α-tocopherol (μg/mL) 10.570 (9.848, 11.293) 10.517 (10.210, 10.825) 0.895
Folate (μg/L) 5.787 (4.805, 6.768) 6.313 (5.895, 6.730) 0.334
Erythrocyte
SOD (U/g Hb) 31.676 (30.550, 32.803) 31.444 (30.980, 31.908) 0.708
CAT (U/g Hb) 2.322 (2.228, 2.416) 2.365 (2.326, 2.404) 0.409
GSH-PX (U/g Hb) 26.344 (24.455, 28.233) 25.905 (25.127, 26.683) 0.673
GST (U/g Hb) 0.352 (0.315, 0.389) 0.335 (0.320, 0.351) 0.408
GR (U/g Hb) 0.593 (0.548, 0.637) 0.547 (0.529, 0.566) 0.068
Cognition
Moca score 25.975 (25.284, 26.667) 26.467 (26.177, 26.757) 0.199

General linear model used. Data are presented as the mean (95% CI). For plasma Glu, TG, TC, LDL-C and HDL-C data analysis, factors including gender, age, BMI, smoking, physical activity were adjusted. For erythrocytes antioxidant biomarkers and plasma folate, retinol and α-tocopherol data analysis, factors including gender, age, BMI, smoking and antioxidant supplementation were adjusted. For cognition (MoCA score) analysis, factors including gender, age, BMI, physical activity, education level, living condition, reading time per day and antioxidant supplementation were adjusted. p value < 0.05 was considered as significance.