Table 1.
Effect of PknB-PASTA overexpression on antimicrobial susceptibility of M. smegmatis.
strain | minimum inhibitory concentration against antibiotic (µM) |
||||||
---|---|---|---|---|---|---|---|
rifampicin | streptomycin | ethambutol | meropenem | clavulanate | meropenem+clavulanatea | ampicillin | |
MIND | 1.2 | 0.4 | 2.5 | 13–19.5 | >1000 | 6.5–13.0 | 140–170 |
PknB1 | 1.2 | 0.4 | 2.5 | 13–19.5 | >1000 | 6.5–13.0 | 140–170 |
TMP | 1.2 | 0.4 | 2.5 | 6.5 | 150–200 | 0.13 | 30–45 |
aClavulanate was added at a concentration of 100 µM.